I had a 67 years ago with a 250 in it and it simply used the Maverick mounts. In one other customers he cut the stock mounts and re bent them to fit. The 250 block is about 2"'s taller than a 170/200 in order to get the added cubes using a longer stroke, much the same as a 351W is also taller. The front to back dimensions are identical to a 144/170 or a 200. If you are installing it in an early you will have a tough time as the early doghouse is 1 3/4" shorter in height and the 250 is about 2" taller in height than them. Add the shorter doghouse height in addition to the taller block and you may have some issues. I would consider if a van to simply use a late doghouse with hump in the rear to begin with??? If you mount the cross member as I do below, it will not matter if it is an early or a late truck itself as you are copying the late frame mount location anyways. Also, as a larger motor, besides the V8/big six bellhousing pattern its well advised to also use a larger radiator. With the late doghouse also being taller, using it would also allow you to use the taller 240 radiator and not have it as low to the ground.
The early single inboard frame mount is about 4",s rear ward of the late mount location. An early with one single inboard frame mount. When I install a V8 in an early I with my V8 cross member (or a big six for that matter) I use the front bolt hole of your existing early inboard mount and use it to bolt up to the rear bolt hole of the late cross member. This places the front of the oil pan so that it will not hit the tie rod. Then I add one single mount hole for that forward bolt hole of the late cross member. This completes the inboard mounting. Regardless of whose or what, you need to add the outboard frame mount no matter what and after placing it this way the outboard mounts is easy.
YOU NEED TO PAY ATTENTION to the fact that the sides of the frame rails ARE NOT 90 DEGREES. I have been posting that forever. They ARE TAPERED!!!!! this means you cannot use a piece of angle iron as the bottom will stick down at an angle and NOT PARALEL with the bottom of the frame.
I spent a great deal of time dialing in all of the drive line angles as well as engine height to get it perfect and built that into my jig fixture. Also, my own motor mount combination to get rid of past said install problems,,,, LOL. You also need to set your left to right center as well a also for the engine to be level. On this setup I used the bottom of the engine block to measure it accurately. On the six you can use either the block surface or the oil pan surface to get it level. When I say level, it should read equal to the floor board on each side of the truck. The truck will never be level, ever and so the only constant measurement will be the floor of the truck.
Lately, I have been cutting out frame mounts to sell with my cross members, however the old way that I used to make them was to construct and build them out of two pieces of metal as I installed them. To do that, I mounted them as I said above,, and then welded in a frame plate, and then mounted the bottom piece to the new cross member. When doing it this way, I purposely left a large bottom gap between the two pieces. Then when I welded it in place I also got a piece of the frame at the same time, essentially welding three pieces together as one, all at the same time. This way this piece came out perfectly flush and parallel with the bottom of the frame. Also, when you bolt it all up to weld,, weld in the nuts on the top so that you don't have to use a wrench to hold the nut...
ALL the Ford transmission use the same transmission mount type. Some variations in thickness but all using the same bolt pattern on the bottom of the transmission. Bottom mount C4, C6 or an AOD or a manual,, all the same bolt spread. The one above is a C6 with a short solid output tail stock. The distance from the bellhousing to the center line of a C4 is identical for either a V8 or a six cylinder. With that I designed and have been making a transmission cross member for many years now that works very well. It is self adjusting in angle as well as width and when used with either my V8 cross member or the stock cross member you can set the bellhousing clearance as well as your desired drive line angle WHERE YOU WANT IT TO BE. The engine angle and drive line angle are already built into all of the cross members to include mine also. You should NOT have to drop the engine height, even in an early. With the above setup the bellhousing will just clear the rear of the doghouse floor if done correctly. If a person is really concerned about it,, I sell also the floor humps to add even more clearance if wanted.
vic